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产品介绍
产品介绍
产品信息
抗原名称
West Nile Virus (WNV)
宿主
E. coli
产品详情
试剂盒
商品描述
West Nile virus (WNV) is a member of the flavivirus genus, which contains many significant human pathogens including Dengue virus (Den), Japanese Encephalitits virus (JE), and Yellow Fever virus (YF). WNV is a small, enveloped virus with a single stranded, positive sense 11kb RNA genome, which encodes a polyprotein precursor. This polyprotein must be cleaved co- and post-translationally to produce ten functional proteins: three structural (C, prM and E) and 7 nonstructural (NS1, NS2A, NS2B, NS3, NS4A,NS4B and NS5). WNV NS3 protease is absolutely essential (along with viral-encoded cofactor NS2B) for post-translational cleavage and viral replication. As a result, this protease is a potential therapeutic target
分子量
32 kDa
纯度
≥95% by SDS-PAGE
浓度
100 µg/ml
形式
In solution
应用
实验应用
FRET,Protease activity
反应种属
West Nile Virus
目标/特异性
Recombinant WNV NS3 protease (residues 1 to 184)
背景
研究领域
Immunology and Infectious disease
制备和贮存
保存方式
Store at -80°C. Avoid repeated freeze-thaw cycles.25 mM Tris-HCl, pH 7.5, 150 mM NaCl
数据库链接
UniProt ID
Q9Q6P4
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