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Plantamajoside
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产品介绍
产品介绍
产品信息
简单描述
Plantamajoside is a phenylethanoid that has been found in P. lanceolata and has diverse biological activities, including antioxidative, anticancer, and anti-inflammatory properties.1,2,3 It scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH; Item No. 14805) radicals in a cell-free assay (IC50 = 11.8 µM). It also inhibits 5-lipoxygenase (5-LO) and 15-LO (IC50s = 0.375 and 96 µM, respectively).1,2 Plantamajoside decreases viability of TE-1 esophageal squamous cell carcinoma (ESCC) cells when used at concentrations ranging from 20 to 320 µg/ml, as well as inhibits LPS-induced epithelial-to-mesenchymal transition (EMT) in Eca-109 and TE-1 cells and decreases phosphorylated NF-κB levels in TE-1 cells.3 Plantamajoside (3 mg/ear) inhibits mouse ear edema induced by arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) by 25%.1WARNING This product is not for human or veterinary use.
商品描述
A phenylethanoid with diverse biological activities
分子量
640.6
纯度
≥95%
产品类型
Biochemicals/Antioxidants/Small Molecule Inhibitors/TNF-α/NF-κB Signaling,Natural Products
背景
别名
Formal_Name:2-(3,4-dihydroxyphenyl)ethyl 3-O-β-D-glucopyranosyl-β-D-glucopyranoside 4-[(2E)-3-(3,4-dihydroxyphenyl)-2-propenoate]
研究领域
Cancer/Cell Death/Cell Signaling/NF-κB Signaling/Transcription Factors/NF-κB,Immunology & Inflammation/Inflammatory Lipid Mediators,Lipid Biochemistry,Oxidative Stress & Reactive Species/Antioxidant Activity/Reactive Oxygen/Non-Enzymatic
结构式
OC1=C(O)C=CC(CCO[C@@H]2O[C@H](CO)[C@@H](OC(/C=C/C3=CC(O)=C(O)C=C3)=O)[C@H](O[C@@]4([H])[C@H](O)[C@@H
分子式
C29H36O16
CAS号
104777-68-6
制备和贮存
保存
≥ 4 years
溶解方法
DMF: 50 mg/ml
DMSO: 33 mg/ml
Ethanol: 10 mg/ml
PBS (pH 7.2): 10 mg/ml
保存方式
-20°C
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