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产品介绍
产品信息
纯化方式
>96% (HPLC)
抗原名称
TRPV1 channels, CB1 receptors
来源纯化
Synthetic
产品详情
An Agonist of TRPV1 Channels and a Ligand of CB1 Receptors
商品描述
Arvanil (#A-335) is a highly pure, synthetic, and biologically active compound.
分子量
439.64
生物活性
Arvanil is an agonist of TRPV1 channels (EC50 = 0.5 nM), a ligand of CB1 receptors (Ki = 0.25-0.5 μM), and an inhibitor of anandamide accumulation (IC50 = 3.6 µM). In vivo it demonstrates vasodilator, analgesic, and anti-inflammatory properties. Arvanil inhibits human breast cancer cell proliferation and the growth of astrocytoma xenograft tumors in mice1-3.
可溶性
Soluble in ethanol and DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
浓度
1 nM – 1 µM.
背景
别名
N-Vanillylarachidonamide
分子式
C28H41NO3.
CAS号
128007-31-8
制备和贮存
存储溶液
Up to four weeks at 4°C or three months at -20°C.
保存方式
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored desiccated at -20°C.
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