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A6770

产品介绍
产品介绍
产品信息
简单描述
A6770 is an inhibitor of sphingosine-1-phosphate (S1P) lyase.1 It induces accumulation of [3H]sphinganine-1-phosphate ([3H]dhS1P), an S1P lyase substrate, in IT-79MTNC3 cells that endogenously express high levels of S1P lyase (EC50 = <0.01 µM), an effect that is reduced in the presence of vitamin B6 (EC50 = <100 µM).WARNING This product is not for human or veterinary use.

商品描述
An inhibitor of S1P lyase

分子量
140.1

纯度
≥98%

产品类型
Biochemicals/Small Molecule Inhibitors/Sphingolipid Turnover

背景
别名
Formal_Name:1-[5-(hydroxymethyl)-1H-imidazol-2-yl]-ethanone

研究领域
Endocrinology & Metabolism/Cofactors & Vitamins,Lipid Biochemistry/Sphingolipids
结构式
OCC1=CN=C(C(C)=O)N1

分子式
C6H8N2O2

CAS号
1331754-16-5

制备和贮存
保存
≥ 4 years

溶解方法
DMF: 30 mg/ml
DMSO: 30 mg/ml
PBS (pH 7.2): 10 mg/ml

保存方式
-20°C
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