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NS-1619
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产品介绍
产品介绍
产品信息
纯化方式
>95%
抗原名称
KCa1.1 K+ channels, SERCA pumps
来源纯化
Synthetic
商品描述
NS-1619 (#N-105) is a highly pure, synthetic, and biologically active compound.
分子量
362.2
生物活性
NS-1619 is a potent and selective KCa1.1 (BK, slo, Large conductance Ca2+-activated K+) channel modulator (enhancer)1. NS-1619 was effective in eliciting and enhancing KCa1.1 channels in smooth muscle as well as in neurons with maximal effects at concentrations around 30 μM1,2. NS-1619 was used in vivo by intracarotid infusion and significantly enhanced blood tumor barrier permeability in the brain tumor area but not in normal brain tissue3.
可溶性
DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
浓度
100 nM - 100 μM.
形式
Lyophilized
组成成分
95%1-(2-羟基-5-(三氟甲基)苯基)-5-(三氟甲基)-1H-苯并[D]咪唑-2(3H)-酮，5%其他杂质
背景
分子式
C15H8F6N2O2.
CAS号
153587-01-0
制备和贮存
存储溶液
Up to four weeks at 4°C or three months at -20°C.
保存方式
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
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