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DMAB-anabaseine dihydrochloride

产品介绍
产品介绍
产品信息
纯化方式
>98%

抗原名称
nAChR

来源纯化
Synthetic

商品描述
DMAB-anabaseine dihydrochloride (#D-110) is a highly pure, synthetic, and biologically active compound.

分子量
364.3

生物活性
DMAB-anabaseine dihydrochloride is a partial agonist of α7 nicotinic acetylcholine receptors (nAChR) and antagonist of α4/β2 nAChR1. It blocks the acetylcholine induced α7 current with IC50 ~5 µM2. DMAB-anabaseine dihydrochloride can also displace isotopic (-)-cytisine and α-bungarotoxin binding to rat brain membranes with high affinity3.

可溶性
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).

浓度
0.1-10 µM.

形式
Lyophilized

背景
别名
3-(4)-Dimethylaminobenzylidine anabaseine

分子式
C19H21N3*2HCl.

CAS号
154149-38-9

制备和贮存
存储溶液
Up to one week at 4°C or six months at -20°C.

保存方式
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
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