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Phalloidin
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产品介绍
产品介绍
产品信息
宿主
无
简单描述
A probe for F-actin
商品描述
Phalloidin is a natural mycotoxin first isolated from the death cap mushroom, A. phalloides. It binds F-actin and stabilizes actin fibers.1,2 Fluorescently labeled phalloidin is commonly used to stain F-actin in cells.3,4
分子量
788.9
纯度
≥98%
组成成分
二羟鬼笔毒肽≥98%杂质≤2%
背景
别名
NSC 523214
结构式
O=C([C@@H](NC([C@@H]1C[C@H](O)CN1C([C@H]2NC([C@H](NC([C@H](C)NC([C@@H]3C[C@@](C)(O)CO)=O)=O)[C@@H](O)C)=O)=O)=O)C)N[C@@H](CC4=C(SC2)NC5=C4C=CC=C5)C(N3)=O
分子式
C35H48N8O11S
CAS号
17466-45-4
制备和贮存
保存
≥ 4 years
溶解方法
DMF: 10 mg/ml
DMSO: 10 mg/ml
Ethanol: 10 mg/ml
Water: 0.5 mg/ml (warm)
保存方式
-20°C
文献
文献
1.Lengsfeld, A.M.,Löw, I.,Wieland, T., et al. Interaction of phalloidin with actin. Proc. Natl. Acad. Sci. USA 71(7), 2803-2807 (1974).
2.Löw, I.,Dancker, P., and Wieland, T. Stabilization of F-actin by phalloidin. Reversal of the destabilizing effect of cytochalasin B. FEBS Lett. 54(2), 263-265 (1975).
3.Wulf, E.,Deboben, A.,Bautz, F.A., et al. Fluorescent phallotoxin, a tool for the visualization of cellular actin. Proc. Natl. Acad. Sci. USA 76(9), 4498-4502 (1979).
4.Jumat, M.R.,Nguyen Hong, T.,Wong, P., et al. Imaging analysis of human metapneumovirus-infected cells provides evidence for the involvement of F-actin and the raft-lipid microdomains in virus morphogenesis. Virol.J. 11, (2014).
2.Löw, I.,Dancker, P., and Wieland, T. Stabilization of F-actin by phalloidin. Reversal of the destabilizing effect of cytochalasin B. FEBS Lett. 54(2), 263-265 (1975).
3.Wulf, E.,Deboben, A.,Bautz, F.A., et al. Fluorescent phallotoxin, a tool for the visualization of cellular actin. Proc. Natl. Acad. Sci. USA 76(9), 4498-4502 (1979).
4.Jumat, M.R.,Nguyen Hong, T.,Wong, P., et al. Imaging analysis of human metapneumovirus-infected cells provides evidence for the involvement of F-actin and the raft-lipid microdomains in virus morphogenesis. Virol.J. 11, (2014).
数据库链接
UN No.
3462
参考图片
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