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产品介绍
产品介绍
产品信息
简单描述
C6 L-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides.1,2 C6 L-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM).3 It is metabolically inactive and, unlike C6 L-erythro ceramide (Item No. 24388), C6 L-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase.2 C6 L-threo Ceramide enhances IL-4 production induced by phorbol 12-myristate 13-acetate (PMA; Item No. 10008014) in EL4 T cells when used at a concentration of 10 μM.4 [Matreya, LLC. Catalog No. 1828]WARNING This product is not for human or veterinary use.
商品描述
A bioactive sphingolipid
分子量
397.6
纯度
≥98%
产品类型
Biochemicals,Lipids/Sphingolipids
背景
别名
Formal_Name:N-[(1S,2S,3E)-2-hydroxy-1-(hydroxymethyl)-3-heptadecen-1-yl]-hexanamide;Synonyms:L-threo Cer(d18:1/6:0) L-threo Ceramide (d18:1/6:0) N-hexanoyl-L-threo-Sphingosine
研究领域
Cancer/Cell Death,Immunology & Inflammation/Adaptive Immunity,Lipid Biochemistry/Sphingolipids
结构式
OC[C@@H]([C@@H](O)/C=C/CCCCCCCCCCCCC)NC(CCCCC)=O
分子式
C24H47NO3
CAS号
189894-80-2
制备和贮存
保存
≥ 4 years
溶解方法
Chloroform: Soluble
DMF: 5 mg/ml
DMSO: Soluble
Ethanol: Soluble
保存方式
-20°C
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