L-Isoleucine-13C6

L-Isoleucine-13C6 is intended for use as an internal standard for the quantification of L-isoleucine by GC- or LC-MS. L-Isoleucine is an essential and branched-chain amino acid.1 It is an isomer of L-leucine (Item No. 34342) and a diastereomer of L-alloisoleucine (Item No. 34904) that functions as a nitrogen donor and has roles in glucose consumption, fatty acid metabolism, and immune function.1,2 Urinary levels of L-isoleucine are increased in patients with deficiencies in β-ketothiolase, short/branched-chain specific acyl-CoA dehydrogenase (SBCAD), or 2-methyl-3-hydroxybutyryl-CoA dehydrogenase (MHBD), inborn errors of metabolism characterized by episodic ketoacidosis and neurological impairments.3WARNING This product is not for human or veterinary use.

An internal standard for the quantification of L-isoleucine

137.1

≥95%

Biochemicals/Amino Acids/Natural/Analytical Standards/Isotopically Labeled Standards/13C

Mass Spectrometry

Formal_Name:L-isoleucine-1,2,3,3′,4,5-13C6;Synonyms:L-(+)-Isoleucine-13C6

[13CH3][13CH2][13C@H]([13CH3])[13C@H](N)[13C](O)=O

[13C]6H13NO2

201740-82-1

≥ 4 years

Water: Soluble