L-Arginine-13C6 (hydrochloride)

L-Arginine-13C6 is intended for use as an internal standard for the quantification of L-arginine (Item No. 23703) by GC- or LC-MS. L-Arginine is an amino acid and a precursor of nitric oxide (NO).1 L-Arginine is a substrate for NO synthase that is oxidized to form NO and L-citrulline. It enhances NO release induced by bradykinin (Item No. 37408) or A23187 (Item No. 11016) in porcine aortic endothelial cells.2 L-Arginine (30 and 300 mg/kg, i.v.) induces dilation of pial arterioles and increases cerebral blood flow in normotensive and spontaneously hypertensive rats.3 It also reduces infarct size by 35 and 28% in normotensive and spontaneously hypertensive rats, respectively, following middle cerebral artery occlusion.WARNING This product is not for human or veterinary use.

An internal standard for the quantification of L-arginine

216.6

≥95%

Biochemicals/Amino Acids/Natural/Analytical Standards/Isotopically Labeled Standards/13C

Mass Spectrometry

Formal_Name:L-arginine-guanidino,1,2,3,4,5-13C6 monohydrochloride;Synonyms:L-(+)-Arginine-13C6

N=[13C](N)N[13CH2][13CH2][13CH2][13C@H](N)[13C](O)=O.Cl

[13C]6H14N4O2 • HCl

201740-91-2

≥ 4 years

Water: soluble