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产品介绍
产品介绍
产品信息
简单描述
An inhibitor of ABHD11
商品描述
ML-226 is an inhibitor of α/β hydrolase domain-containing protein 11 (ABHD11) that inhibits ABHD11 in vitro and in situ (IC50s = 15 and 0.68 nM, respectively).1 It is 100-fold selective for ABHD11 over approximately 20 other serine hydrolases. ML-226 covalently carbamoylates the active site serine of ABHD11. It can be used as an anti-probe for ML-211 (Item No. 17630), an inhibitor of the protein palmitoyl thioesterases lysophospholipase 1 (LYPLA1) and LYPA2.2
分子量
390.5
纯度
≥98%
背景
结构式
O=C(N1N=CC(C(C2=CC=CC=C2)(O)C3=CC=CC=C3)=N1)N4C(CC)CCCC4
分子式
C23H26N4O2
CAS号
2055172-43-3
制备和贮存
保存
≥ 2 years
溶解方法
DMF: 30 mg/mL
DMSO: 30 mg/mL
DMSO:PBS(pH 7.2) (1:4): 0.2 mg/mL
Ethanol: 10 mg/mL
保存方式
-20°C
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