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LEI-110
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产品介绍
产品介绍
产品信息
简单描述
LEI-110 is an inhibitor of adipose phospholipase A2 (AdPLA2; IC50 = 100 nM).1 It also inhibits HRas-like suppressor 2 (HRASL2), retinoid acid receptor responder protein 3 (RARRES3), and calcium-independent N-acyltransferase (iNAT; IC50s = 158, 158, and 25 nM, respectively). LEI-110 (10 µM) decreases arachidonic acid (Item Nos. 90010 | 90010.1 | 10006607) levels in U2OS cells expressing human AdPLA2 and prevents oleic acid-induced increases in lipid droplet formation in HepG2 cells.WARNING This product is not for human or veterinary use.
商品描述
An AdPLA2 inhibitor
分子量
456.5
纯度
≥98%
产品类型
Biochemicals/Small Molecule Inhibitors/Phospholipases
背景
别名
Formal_Name:α-oxo-N-[2-[4-[[5-(trifluoromethyl)-2-pyridinyl]oxy]phenyl]ethyl]-benzenepentanamide
研究领域
Lipid Biochemistry/Glycerophospholipids/Phospholipases
结构式
O=C(C(CCCC1=CC=CC=C1)=O)NCCC2=CC=C(C=C2)OC3=CC=C(C(F)(F)F)C=N3
分子式
C25H23F3N2O3
CAS号
2313525-90-3
制备和贮存
保存
≥ 4 years
溶解方法
Ethanol: soluble
保存方式
-20°C
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