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β-Carboline-1-carboxylic Acid
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产品介绍
产品介绍
产品信息
简单描述
An alkaloid with diverse biological activities
商品描述
β-Carboline-1-carboxylic acid is an alkaloid that has been found in P. quassioides and has diverse biological activities.1,2,3 It reduces LPS-induced increases in MCP-1, TNF-α, IL-6, and IL-1β levels in RAW 264.7 cells when used at a concentration of 15 µg/ml and inhibits the epithelial-to-mesenchymal transition (EMT) induced by TGF-β1 in A549 cells.2 β-Carboline-1-carboxylic acid induces cytotoxicity in CT26.WT, K562, and SGC-7901 cells (IC50s = 14.96, 22.11, and 19.7 µg/ml, respectively) but not HepG2 or A549 cells (IC50s = 36.41 and 41.51 µg/ml, respectively).1 It also inhibits cAMP phosphodiesterase with an IC50 value of 96 µM.3
分子量
212.2
纯度
≥95%
背景
别名
1-Formic Acid-β-carboline
结构式
O=C(C1=NC=CC2=C1NC3=C2C=CC=C3)O
分子式
C12H8N2O2
CAS号
26052-96-0
制备和贮存
保存
≥ 4 years
溶解方法
DMSO: soluble
Methanol: soluble
保存方式
-20°C
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