3,5-DHBA (50 mg)

7424

Selective HCA₁ agonist

154.12

3,5-Dihydroxybenzoic acid

Selective agonist of hydroxycarboxylic acid receptor 1 (HCA₁, also known as GPR81) (EC₅₀ ~150 μM). Inhibits lipolysis in wild-type mouse adipocytes. Displays minimal activity at HCA₂ (at concentrations >10 mM) and no activity at HCA₃, free fatty acid receptor (FFAR) 2 or FFAR3.

≥99% (HPLC)

Soluble to 100 mM in water and to 100 mM in DMSO

OC1=CC(O)=CC(C(O)=O)=C1

C₇H₆O₄

99-10-5