BCTC

BCTC

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品牌: Alomone
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分子量:
372.9
CAS号:
393514-24-4
产品介绍
产品信息
纯化方式
>99% (HPLC)
抗原名称
TRPV1 and TRPM8 channels
来源纯化
Synthetic
商品描述
BCTC (#B-110) is a highly pure, synthetic, and biologically active compound.
分子量
372.9
生物活性
BCTC is a potent and selective antagonist of TRPV1 channels, shown to inhibit capsaicin-, pH- and PKC-induced responses of mouse TRPV1 with IC50 of 1.3, 0.59 and 0.37 nM, respectively.1,2 BCTC is also a blocker of TRPM8 channels, inhibiting rat TRPM8-mediated menthol and cold-evoked Ca2+ response with IC50 of 0.6 µM.3
可溶性
1-10 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
浓度
1 nM – 100 nM.
形式
Lyophilized
背景
别名
N-(4-tert-butylphenyl)-4-(3-chloropyridin-2-yl)piperazine-1-carboxamide
分子式
C20H25ClN4O.
CAS号
393514-24-4
制备和贮存
存储溶液
Up to four weeks at 4°C or three months at -20°C.
保存方式
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
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货号:
B-110-10mg
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