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SKA-31
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产品介绍
产品介绍
产品信息
纯化方式
>98%
抗原名称
KCa2, KCa3.1, TRPM7 channels
来源纯化
Synthetic
商品描述
SKA-31 (#S-120) is a highly pure, synthetic, and biologically active compound.
分子量
200.2
生物活性
SKA-31 is an activator of KCa3.1 and KCa2 channels (EC50 values are 260, 2900, 2900 nM for KCa3.1, KCa2.1 and KCa2.2 respectively)1. Potentiates acetylcholine-induced EDHF-type dilations of mouse carotid arteries and lowers blood pressure in normotensive and hypertensive mice1,2. SKA-31 blocks TRPM73.
可溶性
DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
浓度
0.1-10 µM.
形式
Lyophilized
组成成分
萘并[1,2-D]噻唑-2-胺＞98%，水＜2%
背景
分子式
C11H8N2S.
CAS号
40172-65-4
制备和贮存
存储溶液
Up to four weeks at 4°C or three months at -20°C.
保存方式
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
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