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Capsaicin
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产品介绍
产品信息
纯化方式
>98% (HPLC)
抗原名称
TRPV1 channels
来源纯化
Synthetic
商品描述
Capsaicin (#C-125) is a highly pure, Synthetic, and biologically active compound.
分子量
305.4
生物活性
Capsaicin is one of the most powerful chemical agonists of the TRPV1 (transient receptor potential vanilloid) channel. It is a small lipophilic molecule derived from hot chili peppers that acts on sensory neurons by opening TRPV1, a principal transduction channel for nociception1. Capsaicin acts directly on TRPV12, with half-maximal effective concentration of 711.9 nM in Xenopus oocytes3 and 0.29 μM in HEK293 cells4.
可溶性
Ethanol. Centrifuge all product preparations before use (10000 x g 5 min).
浓度
0.1-10 μM.
形式
Lyophilized
组成成分
(E)-N-[(4-羟基-3-甲氧基苯基)甲基]-8-甲基-6-壬烯酰胺
背景
别名
(E)-Capsaicin, CPS
分子式
C18H27NO3.
CAS号
404-86-4
制备和贮存
存储溶液
Up to one week at 4°C or six months at -20°C.
保存方式
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
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