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产品介绍
产品介绍
产品信息
商品描述
Selective sirtuin inhibitor which does not effect HDAC1 (IC50 = 131 M, 38 M and 68 M for SIRT1, SIRT2 and Sir2P respectively) (ref 1). Induces apoptotic and autophagic cell death in MCF-7 human breast cancer cell lines (ref 2). Suppresses survivin expression which correlates with decreased viability in HT29 colon cancer cells (ref 3). Displays pro-inflammatory effects in adipocytes (ref 4).
分子量
394.5
纯度
>98% (TLC); NMR (Conforms)
外观
Yellow powder. May be dissolved in DMSO (35 mg/ml); Ethanol (10 mg/ml).
备注
/
背景
别名
2-[(2-Hydroxynaphthalen-1-ylmethylene)amino]-N-(1-phenethyl)benzamide
分子式
C26H22N2O2
CAS号
410536-97-9
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