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5-LO (33)

产品介绍
产品信息
宿主
mouse

简单描述
抗-5-LO抗体(33)是小鼠单克隆IgG1 κ 5-LO抗体, 在13篇文献中引用,规格为200 µg/mlraised against a C-terminus portion of 5-LO of human origin推荐用于 mouse, rat, human 和 Arabadopsis 来源的5-LO WB, IP 和 IF检测; not recommended for IP关于如何获取5-LO (33): sc-136195的免费10 µg小样,联系我们技术服务部门 (或者您当地的代理商)了解详情。m-IgG Fc BP-HRP, m-IgG1 BP-HRP 和 m-IgGκ BP-HRP 是 5-LO Antibody (33) for WB 的首选应用二抗。这些试剂现在以套装形式提供5-LO Antibody (33)。 (见下方订购信息).
查看产品引用文献(12) 5-LO Antibody (33) is a high quality monoclonal 5-LO antibody (also designated LOX5 antibody, Arachidonate 5-Lipoxygenase antibody, Polyunsaturated Fatty Acid 5-Lipoxygenase antibody, 5-LOX antibody, LOG5 antibody, Arachidonic Acid 5-Lipoxygenase antibody, Leukotriene A4 Synthase antibody, 5-Lipoxygenase antibody, LOX-5 antibody, or 5LPG antibody) suitable for the detection of the 5-LO protein of mouse, rat, human and a origin. 5-LO Antibody (33) is available as the non-conjugated anti-5-LO antibody. 5-lipoxygenase (5-LO) is expressed primarily in polymorphonuclear leukocytes, macrophages, and mast cells. 5-LO performs the first two catalytic reactions in the biosynthesis of leukotrienes, lipid metabolites that induce contractions of airway smooth muscle and increase vascular permeability during anaphylaxis. The cellular localization of 5-LO varies between cell types. In activated blood polymorphonuclear leukocytes 5-LO undergoes calcium dependent translocation from the cytosol to the nuclear envelope. In alveolar macrophages, the majority of 5-LO is localized in the nucleus and, upon activation of these cells, intranuclear 5-LO binds to the nuclear membrane. This intracellular shuttling of 5-LO is dependent on the association with various signaling molecules, phosphorylation and the presence of a distinct nuclear localization signal, which is encoded at the amino terminus of 5-LO.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

克隆类别
Replacement monoclonal antibody for: sc-8885, sc-8886, sc-20785.

组成成分
IGG-免疫球蛋白G型抗体

基因

数据库链接
Entrez-Gene ID
240;11689

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