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产品介绍
产品介绍
产品信息
纯化方式
>98% (HPLC)
抗原名称
α7 nAChR
来源纯化
Synthetic
商品描述
PNU-120596 (#P-350) is a highly pure, synthetic, and biologically active compound.
分子量
311.72
生物活性
PNU-120596 is a potent and selective type-II positive allosteric modulator of α7 nicotinic acetylcholine receptors, shown to potentiate α7 currents in X. Laevis oocytes and in SH-EP1 cells with EC50 values of 1.6 µM and 216 nM, respectively1-2. Neuroprotective in vivo3.
可溶性
Soluble to 100 mM in DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
浓度
0.3-10 µM.
形式
Lyophilized
背景
分子式
C13H14ClN3O4.
CAS号
501925-31-1
制备和贮存
存储溶液
Store at -20°C. It is recommended to prepare solutions afresh on the day of use, or aliquot stock solutions stored at -20°C to prevent repeated thawing and freezing.
保存方式
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at +4°C.
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