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Penicillide
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产品介绍
产品介绍
产品信息
简单描述
Penicillide is a fungal metabolite originally isolated from Penicillium that has diverse biological activities.1,2,3,4,5 It is an inhibitor of calpain 2/m-calpain (IC50 = 7.1 µM) and acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 22.9 µM).2,3 It is also an antagonist of oxytocin receptors (IC50 = 67 µM).4 Penicillide inhibits RNA synthesis in P388 murine leukemia cells.5WARNING This product is not for human or veterinary use.
商品描述
A fungal metabolite with diverse biological activities
分子量
372.4
纯度
≥95%
产品类型
Biochemicals/Small Molecule Inhibitors/Sterol Biosynthesis,Natural Products/Microbial Metabolites
背景
别名
Formal_Name:11-hydroxy-3-[(1S)-1-hydroxy-3-methylbutyl]-4-methoxy-9-methyl-5H,7H-dibenzo[b,g][1,5]dioxocin-5-one;Synonyms:Vermixocin A
研究领域
Cell Biology/Proteolysis/Cytosolic & Secreted Proteases,Lipid Biochemistry/Acyl-CoAs/Sterol Lipids
结构式
COC1=C2C(OC(C(O)=CC(C)=C3)=C3COC2=O)=CC=C1[C@@H](O)CC(C)C
分子式
C21H24O6
CAS号
55303-92-9
制备和贮存
保存
≥ 4 years
溶解方法
DMSO: soluble
保存方式
-20°C
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