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Bilirubin
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产品介绍
产品介绍
产品信息
简单描述
Bilirubin is a yellow breakdown product of heme catabolism, formed when heme is cleaved by heme oxygenase.1 This reaction produces carbon monoxide and biliverdin, which is rapidly reduced to bilirubin by biliverdin reductase. Bilirubin has key roles as a free radical scavenger with antioxidant and anti-inflammatory actions.1 Free and albumin-bound bilirubin can also scavenge nitric oxide (NO) and NO-related species. Unconjugated bilirubin is highly water-insoluble and must be conjugated with glucuronides to become water soluble and subsequently excreted by the liver and kidney.1WARNING This product is not for human or veterinary use.
商品描述
A breakdown product of heme catabolism
分子量
584.7
纯度
≥95%
产品类型
Biochemicals/Antioxidants
背景
别名
Formal_Name:2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic acid;Synonyms:Hematoidin NSC 26685
研究领域
Endocrinology & Metabolism/Biliary System,Immunology & Inflammation,Oxidative Stress & Reactive Species/Antioxidant Activity/Reactive Nitrogen
结构式
CC1=C(/C=C2NC(C(C=C)=C\2C)=O)NC(CC3=C(CCC(O)=O)C(C)=C(/C=C4NC(C(C)=C\4C=C)=O)N3)=C1CCC(O)=O
分子式
C33H36N4O6
CAS号
635-65-4
制备和贮存
保存
≥ 4 years
溶解方法
Chloroform: 5 mg/ml
DMF: 0.1 mg/ml
DMSO: 0.2 mg/ml
保存方式
-20°C
文献
文献
1.Levitt, D.G., and Levitt, M.D. Quantitative assessment of the multiple processes responsible for bilirubin homeostasis in health and disease. Clincal and Experimental Gastroenterology 7, 307-328 (2014).
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