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产品介绍
产品介绍
产品信息
纯化方式
>99% (HPLC)
抗原名称
L-type Ca2+ channels
来源纯化
Synthetic
商品描述
(±)-Bay K8644 (#B-350) is a highly pure, synthetic, and biologically active compound.
分子量
356.3
生物活性
(±)-Bay K8644 is a dihydropyridine that acts as an L-type, voltage-gated Ca2+ channel agonist. The (-)-enantiomer has strong Ca2+ channel agonist properties, whereas the (+)-enantiomer has weak Ca2+ channel antagonist activity. The net activity of the racemic mix is L-type channel opening. In the presence of this agonist, channels tend to open for longer periods causing a large increase in the channel microscopic response1-4. (±)-Bay K8644 is also an inhibitor (by increasing the inactivation) of a Shaker KV channel5.
可溶性
Ethanol, methanol or DMSO. Centrifuge all product preparations before use (10000 x g 5 min).
浓度
1-5 μM.
形式
Lyophilized
背景
分子式
C16H15F3N2O4.
CAS号
71145-03-4
制备和贮存
存储溶液
Up to four weeks at 4°C or three months at -20°C.
保存方式
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
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