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Isradipine
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产品介绍
产品介绍
产品信息
简单描述
Isradipine is a 2,4-dihydropyridine selective agonist and calcium channel protein inhibitor. Research has indicated that Isradipine has anti-atherosclerotic effects in animals and improves endothelium-mediated nitric oxide (NO)-dependent vasodilation in vitro. Additional studies indicate that Isradipine may provide a neuroprotective effect in a rat model of focal ischemia and that Isradipine produces a dose-dependent sparing of dopamine neuronal fibers and cell bodies.
参考文献 1. Chandra, S., et al. 1999. Pharmacology. 58: 292-299. PMID: 10325574 2. Bracht, C., et al. 2001. J. Hypertens. 19: 899-905. PMID: 11393673 3. Ilijic, E., et al. 2011. Neurobiol. Dis. 43: 364-371. PMID: 21515375
分子量
371.4
外观
crystalline powder
应用
实验应用
Isradipine is a selective agonist and calcium channel protein inhibitor
背景
结构式
CC1=C(C(C(=C(N1)C)C(=O)OC(C)C)C2=CC=CC3=NON=C32)C(=O)OC
分子式
C19H21N3O5
CAS号
75695-93-1
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