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产品介绍
产品介绍
产品信息
抗原名称
PKA
商品描述
8-Bromo-cAMP sodium salt (8-Br-Camp sodium salt) is a long-acting derivative of cyclic AMP. It is an activator of cyclic AMP-dependent protein kinase（PKA）, but resistant to degradation by cyclic AMP phosphodiesterase.
分子量
430.08
纯度
＞98%
可溶性
DMSO : 35 mg/mL (81.38 mM), warmed
Water : 80 mg/mL (186.01 mM), warmed
Water : 80 mg/mL (186.01 mM), warmed
外观
off-white powder
In vitro(体外研究)
8-Bromo-cAMP improves the reprogramming efficiency of human neonatal foreskin fibroblast (HFF1) cells. In bronchial epithelial cells, 8-Bromo-cAMP decreases HDE-stimulated tumor necrosis factor (TNF)-α-converting enzyme (TACE; ADAM-17) activity and subsequent TNF-α release.
背景
别名
8-溴腺苷-3‘,5‘-环单磷酸钠
分子式
C10H10BrN5NaO6P
CAS号
76939-46-3
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
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