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产品介绍
产品介绍
产品信息
简单描述
Stobadine is a pyridoindole antioxidant.1 It scavenges hydroxyl, peroxyl, and alkoxyl radicals and quenches singlet oxygen in cell-free assays. Ex vivo, stobadine (2 mg/kg) reduces lipid peroxidation induced by hypoxia and reoxygenation in rat forebrain.2 It improves survival in a rat model of carotid artery ligation-induced cerebral ischemia. Stobadine (1 mg/kg, i.v.) increases myocardial blood flow and decreases infarct area in a dog model of myocardial infarction induced by acute occlusion of the left coronary artery.1 Dietary administration of stobadine (0.05% w/w) delays the development of cataracts and reduces eye lens protein oxidation and plasma levels of malondialdehyde (MDA) in a rat model of diabetes induced by streptozotocin (STZ; Item No. 13104).3WARNING This product is not for human or veterinary use.
商品描述
A pyridoindole antioxidant
分子量
202.3
纯度
≥98%
产品类型
Biochemicals/Antioxidants
背景
别名
Formal_Name:2,3,4,4aR,5,9bS-hexahydro-2,8-dimethyl-1H-pyrido[4,3-b]indole;Synonyms:Stobadin
研究领域
Cardiovascular System/Cardiovascular Diseases/Myocardial Infarction/Stroke,Neuroscience/Neuroprotection/Ischemia/Ophthalmology,Oxidative Stress & Reactive Species/Antioxidant Activity/Lipid Peroxidation/Protein Oxidation/Reactive Oxygen
结构式
CC1=CC=C2N[C@@](CCN(C3)C)([H])[C@@]3([H])C2=C1
分子式
C13H18N2
CAS号
85202-17-1
制备和贮存
保存
≥ 4 years
溶解方法
DMSO: >100 mM
保存方式
-20°C
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