Neuropeptide Y (human, rat)

Neuropeptide Y (NPY) is a peptide abundantly distributed throughout the central and peripheral nervous systems that plays a major role in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion.1 Five subtypes of the NPY receptor have been identified. Subtypes Y1 and Y5 have known roles in the stimulation of feeding while Y2 and Y4 seem to have roles in satiety.1 NPY has also been shown to interact with the immune system, promoting gastrointestinal inflammation, as well as exhibiting an antimicrobial effect against several gut bacteria.2WARNING This product is not for human or veterinary use.

A key neuropeptide of the gut-brain axis

4271.7

≥95%

Biochemicals/Peptides/Neuropeptides/Receptor Pharmacology/Agonists

Synonyms:NPY (human, rat)

NC([C@@H](NC([C@H](CCCNC(N)=N)NC([C@H](CCC(N)=O)NC([C@H](CCCNC(N)=N)NC([C@@]([C@@H](C)O)([H])NC([C@@

90880-35-6

≥ 4 years

DMF: 30 mg/ml DMSO: 30 mg/ml Ethanol: 30 mg/ml PBS (pH 7.2): 10 mg/ml

1.Balasubramaniam, A. Neuropeptide Y family of hormones: Receptor subtypes and antagonists. Peptides 18, 445-457 (1997).
2.Holzer, P.,Reichmann, F. and Farzi, A. Neuropeptide Y, peptide YY and pancreatic polypeptide in the gut-brain axis. Neuropeptides 46(6), 261-274 (2012).