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ADAM12 is a 120kD type I transmembrane glycoprotein member of the metzincin family of proteases. It is synthesized as a 909aa preproprecursor that con
ADAM12 is a 120kD type I transmembrane glycoprotein member of the metzincin family of proteases. It is synthesized as a 909aa preproprecursor that con
品牌： Usbiological
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Purified by immunoaffinity chromatography.
反应种属：
Goat
产品介绍
产品介绍
产品信息
抗原来源
Rat
宿主
Goat
免疫原
Synthetic peptide corresponding to KKTTMEKLRCVHP, from Adam12, at the internal region of the protein (NP_031426.2).
产品用途
Suitable for use in ELISA. Other applications not tested.
简单描述
ADAM12 is a 120kD type I transmembrane glycoprotein member of the metzincin family of proteases. It is synthesized as a 909aa preproprecursor that contains a 25kD proregion (aa29-207) and a 92kD mature molecule. Proteolytic cleavage in the Golgi removes the propeptide prior to cell-surface expression. A 68kD soluble splice form exists in pregnancy where 36aa replace the C-terminal 205aa (705-909). This circulating ADAM12 isoform remains associated with its prodomain via noncovalent linkage, possibly acting as an enzyme regulator. Over aa29-513, human ADAM12 shares 78% and 79% aa identity with bovine and mouse ADAM12, respectively.
同种型
IgG
克隆类别
Polyclonal
纯度
Purified by immunoaffinity chromatography.
形式
Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
应用
实验应用
E
推荐用量
ELISA: 1:4000 Optimal dilutions to be determined by the researcher.
反应种属
Goat
交叉反应性
Mo Po Rt
目标/特异性
Recognizes Adam12. Species sequence homology: Mouse, porcine and rat.
稀释度
ELISA: 1:4000 Optimal dilutions to be determined by the researcher.
制备和贮存
保存方式
Storage_Temp:-20°C
Storage_and_Stability:May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
Entrez-Gene ID
8038, 11489, 679837
Accession
NP_031426.2
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