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产品介绍
产品介绍
产品信息
纯化方式
>98% (HPLC)
抗原名称
KV1.3 K+ channels
序列号
GVPINVSCTGSPQCIKPCKCAGMRFGKCMNRKCHCTPK.
商品描述
Agitoxin-2-Cys-TAMRA (#RTA-420-T) is a highly pure, recombinant, and biologically active conjugated peptide toxin.
分子量
4673 Da
生物活性
Agitoxin-2 is a blocker of Shaker voltage-gated K+ channels as well as the mammalian homologues of Shaker. Agitoxin-2-Cys-TAMRA inhibits KV1.3 channels as potently.
可溶性
Any aqueous buffer. Centrifuge all product preparations before use (10000 x g 5 min).
浓度
50 pM - 10 nM.
形式
Lyophilized
背景
别名
K+ channel toxin α-KTx 3.2, AgTx-2, AgTx2
翻译后修饰
Disulfide bonds between Cys8-Cys28, Cys14-Cys33, Cys18-Cys35. Asp20 mutated to a Cys residue (indicated in bold) which was reacted with 5(6)-TAMRA-C5-maleimide.
分子式
C202H316N58O51S9.
制备和贮存
存储溶液
Up to one week at 4°C or three months at -20°C.
保存方式
Shipped at room temperature. Product as supplied can be stored intact at room temperature for several weeks. For longer periods, it should be stored at -20°C.
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