全部商品分类首页
Aloxistatin
.jpg)
1/2
用小程序，查商品更便捷
产品介绍
产品介绍
产品信息
抗原名称
Cysteine protease
商品描述
Aloxistatin 是一种不可逆的膜透过性cysteine protease 抑制剂。
分子量
342.43
纯度
＞98%
可溶性
DMSO : 6.9 mg/mL (20 mM)
外观
白色粉末
In vitro(体外研究)
Aloxistatin can enter the intact platelet and inhibit proteolysis by inhibiting calpain. Aloxistatin blunts Parathyroid hormone (PTH)-induced cell proliferation and inhibits differentiation osteoblasts in vitro.
In vivo(体内研究)
Aloxistatin (100 mg/kg, p.o.) strongly inhibits the cathepsin B&L activities in the skeletal muscle, heart and liver of hamsters. In spinal cord injury (SCI) rats, Aloxistatin provides neuroprotection in SCI lesion and penumbra. Aloxistatin reduces brain amyloid-β and improves memory deficits in Alzheimer's disease animal models by inhibiting cathepsin B activity.
背景
别名
阿洛司他丁；E64d; E64c ethyl ester
分子式
C17H30N2O5
CAS号
88321-09-9
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
参考图片
声明 ：本官网所有报价均为常温或者蓝冰运输价格，如有产品需要干冰运输，需另外加收干冰运输费。