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产品介绍
产品信息
序列号
Ac-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-D-Arg-NH2
商品描述
ALX 40-4C Trifluoroacetate is a small peptide inhibitor of the chemokine receptor CXCR4, inhibits SDF-1 from binding CXCR4 with a Ki of 1 μM, and suppresses the replication of X4 strains of HIV-1; ALX 40-4C Trifluoroacetate also acts as an antagonist of the APJ receptor, with an IC50 of 2.9 μM.
分子量
1464.74
纯度
98%
可溶性
10 mM in H2O
In vitro(体外研究)
SDF-1-CXCR41 μM (Ki)APJ receptor2.9 μM (IC50)
In vivo(体内研究)
SDF-1-CXCR41 μM (Ki)APJ receptor2.9 μM (IC50)
来源（爱必信）
Synthetic
背景
分子式
C56H113N37O10xC2HF3O2
CAS号
143413-49-4（free base)
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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