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产品介绍
产品信息
商品描述
Amino-PEG11-amine is a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, providing an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer.

分子量
544.68

纯度
95%

可溶性
DMSO:10 mM

In vitro(体外研究)
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

背景
分子式
C24H52N2O11

CAS号
479200-82-3

制备和贮存
保存方式
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
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