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Amino-PEG11-Amine

Amino-PEG11-Amine

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品牌: Absin
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分子式:
C24H52N2O11
分子量:
544.68
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产品介绍
产品介绍
产品信息
商品描述

Amino-PEG11-amine is a PEG-based (12 units) PROTAC linker used to combine two mono diethylstilbestrol (DES)-based ligands, providing an alternative strategy for preparing more selective and active ER antagonists for endocrine therapy of breast cancer.

分子量
544.68
纯度

95%

可溶性
DMSO:10 mM
In vitro(体外研究)
PROTACs contain two different ligands connected by a linker; one of them is a ligand for an E3 ubiquitin ligase and the other one is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
背景
分子式
C24H52N2O11
CAS号
479200-82-3
制备和贮存
保存方式
Store at -20℃ for one year(Powder);Store at 2-4℃ for two weeks;Store at -20℃ for six months after dissolution.
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货号:
abs828967-25mg
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询价
25mg
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