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AMT hydrochloride
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产品介绍
产品介绍
产品信息
商品描述
AMT hydrochloride is a potent, selective, and reversible inhibitor of NOS2 (IC50 = 3.6 nM; approximately 30 and 40 times selective over NOS1 and NOS3, respectively).
分子量
166.67
纯度
≥98%
可溶性
Soluble in water (10 mM), ethanol (~8 mg/ml), DMSO (~8 mg/ml), and DMF (~8 mg/ml).
IC50
eNOS: IC50 = 150 nM (bovine); RAW264.7: IC50 = 22 nM (rat); iNOS: IC50 = 3.6 nM; nNOS: IC50 = 34 nM (rat)
Ki 数据
iNOS : Ki= 4.2 nM (mouse)
背景
别名
2-Amino-5,6-dihydro-6-methyl-4H-1,3-thiazine
分子式
C5H10N2S•HCl
CAS号
21463-31-0
PK值
pKb: 6.98 (Predicted)
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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