Amyloid beta A4 Protein (Amyloid Precursor Protein, Amyloid beta, AAA, Amyloid beta A4 Protein, AD1, PN2, ABPP, APPI, CVAP, ABETA, PN-II, CTFgamma) (F

Recombinant protein corresponding to human Amyloid beta A4 (aa18-249).

Suitable for use in ELISA. Other applications not tested.

This gene encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy). Multiple transcript variants encoding several different isoforms have been found for this gene.

IgG

Polyclonal

Purified by Protein G affinity chromatography.

Suitable for use in ELISA. Other applications not tested.

Optimal dilutions to be determined by the researcher.

Rabbit

Hu

Recognizes human APP.

ABPP,APPI,Alzheimer disease amyloid protein,Cerebral vascular amyloid peptide,PreA4,Protease nexin-II,A4, AD1,APP

P05067