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ANGPTL4 (FITC)
品牌： Usbiological
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对比
咨询纯度：
Purified by immunoaffinity chromatography.
反应种属：
Rabbit
产品介绍
产品介绍
产品信息
荧光素标记
抗原来源
Human
宿主
Rabbit
免疫原
Recombinant protein corresponding to aa26-406 of human ANGPTL4. Subcellular Location: Secreted, Secreted, extracellular space, extracellular matrix
产品用途
Suitable for use in FLISA. Other applications not tested.
简单描述
Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorigenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity. In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation (By similarity).
同种型
IgG
克隆类别
Polyclonal
纯度
Purified by immunoaffinity chromatography.
形式
Supplied as a liquid in 0.01M PBS, pH 7.4, 0.03% Proclin 300, 50% glycerol. Labeled with Fluorescein isothiocyanate (FITC).
应用
实验应用
FLISA
推荐用量
Optimal dilutions to be determined by the researcher.
反应种属
Rabbit
交叉反应性
Hu
目标/特异性
Recognizes human ANGPTL4.
稀释度
Optimal dilutions to be determined by the researcher.
背景
别名
Angiopoietin-related protein 4 (Angiopoietin-like protein 4) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP), ANGPTL4, ARP4 HFARP PGAR
制备和贮存
保存方式
Storage_Temp:-20°C
Storage_and_Stability:Store product at 4°C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20°C. Aliquots are stable at -20°C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: FITC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
数据库链接
UniProt ID
Q9BY76
SwissProt
Q9BY76
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