Anti-B7-2 antibody (DM85), Rabbit mAb

Purified from cell culture supernatant by affinity chromatography

T-lymphocyte activation antigen CD86

Recombinant human B7-2 (Leu26-Pro247) produced by using human HEK293 cells

This gene encodes a type I membrane protein that is a member of the immunoglobulin superfamily. This protein is expressed by antigen-presenting cells, and it is the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. Binding of this protein with CD28 antigen is a costimulatory signal for activation of the T-cell. Binding of this protein with cytotoxic T-lymphocyte-associated protein 4 negatively regulates T-cell activation and diminishes the immune response. Alternative splicing results in several transcript variants encoding different isoforms.

DM85

Liquid. 50% Glycerol; PBS, pH7.4; 0.1% BSA; 0.1% Procline 300

Monoclonal

ELISA (EIA), Flow Cytometry (FC/FACS)

Human

CD86; B7-2; B70; CD28LG2; LAB72; MGC34413

942

P42081 [Other Products]