Anti-B7H3 antibody (DM53), Rabbit mAb

Purified from cell culture supernatant by affinity chromatography

B7-H3 protein

Recombinant human B7H3 (Leu29-Pro245) produced by using human HEK293 cells

The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

DM53

Liquid. 50% Glycerol; PBS, pH7.4; 0.1% BSA; 0.1% Procline 300

Monoclonal

ELISA (EIA), Flow Cytometry (FC/FACS)

Human

B7-H3; CD276; B7 homolog 3; B7H3

80381

Q5ZPR3 [Other Products]