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Anti-B7H3 antibody (DM53), Rabbit mAb

产品介绍
产品介绍
产品信息
纯化方式
Purified from cell culture supernatant by affinity chromatography

抗原名称
B7-H3 protein

免疫原
Recombinant human B7H3 (Leu29-Pro245) produced by using human HEK293 cells

商品描述
The protein encoded by this gene belongs to the immunoglobulin superfamily, and thought to participate in the regulation of T-cell-mediated immune response. Studies show that while the transcript of this gene is ubiquitously expressed in normal tissues and solid tumors, the protein is preferentially expressed only in tumor tissues. Additionally, it was observed that the 3' UTR of this transcript contains a target site for miR29 microRNA, and there is an inverse correlation between the expression of this protein and miR29 levels, suggesting regulation of expression of this gene product by miR29. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

克隆号
DM53

形式
Liquid. 50% Glycerol; PBS, pH7.4; 0.1% BSA; 0.1% Procline 300

产品类型
Monoclonal

应用
实验应用
ELISA (EIA), Flow Cytometry (FC/FACS)

反应种属
Human

背景
别名
B7-H3; CD276; B7 homolog 3; B7H3

制备和贮存
保存方式
Store at -20 degree C for 12 months (Avoid repeated freezing and thawing)
数据库链接
NCBI
80381

UniProt ID
Q5ZPR3
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