Anti-IGFBP2 Mouse mAb

insulin-like growth factor-binding protein 2 isoform c

Purified recombinant fragment of protein IGFBP2 (aa180-328) expressed in E Coli.

Entrez Summary: IGFBP2: insulin-like growth factor binding protein 2. IGFBP2 is a member of the ISGBP family which bind various IGFs. IGFBP2 is overexpressed in a wide spectrum of other cancers, including glioma, prostate cancer, synovial sarcoma, neuroblastoma, colon cancer, adrenocortical cancer, lung cancer, Wilms' tumor, and hepatoblastoma. The overexpression of IGFBP2 also correlates with the aggressiveness of some tumors. IGFBP2 activates the expression of matrix metalloprotease 2, which contributes to cell invasiveness.

1F6F6

Ascitic fluid containing 0.03% sodium azide.

Monoclonal

Western Blot (WB), Immunohistochemistry (IHC)

Human

IBP2; IGF-BP53

3485

P18065 [Other Products]