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产品介绍
产品信息
纯化方式
Affinity purified on immobilized antigen.
宿主
Rabbit
免疫原
Peptide (C)KIRKEFPKTQGQYSGFKYPY, corresponding to amino acid residues 576-595 of rat P2X7 receptor (Accession Q64663). Intracellular, C-terminus.
简单描述
A Rabbit Polyclonal Antibody to P2X7 Receptor Conjugated to the Fluorescent Dye ATTO-550
商品描述
Anti-P2X7 Receptor Antibody (#APR-004) is a highly specific antibody directed against an epitope of the rat protein. The antibody can be used in western blot, immunoprecipitation, immunocytochemistry, and immunohistochemistry applications. It has been designed to recognize P2X7 purinergic receptor from rat, mouse, and human samples.
同种型
Rabbit IgG.
纯度
Affinity purified on immobilized antigen.
形式
Lyophilized
组成成分
抗蛋白抗体
基因
P2RX7
应用
实验应用
IF, IHC
反应种属
H, M, R
背景
别名
Purinergic receptor P2X7, P2RX7, P2Z, ATP receptor
背景
The P2X7 receptor is a member of the ionotropic P2X receptor family that is activated by ATP.
To date, this family is composed of seven receptor subtypes, named P2X1-P2X7, all of which have been cloned.
The various P2X receptors show distinct expression patterns. P2X1-6 receptors have been found in the central and peripheral nervous system, while the P2X7 receptor is found in cells of the immune system, particularly in antigen-presenting cells, and microglia.
The P2X7 receptor mediates the release of proinflamatory cytokines and stimulation of transcription factors and may also play an important role in apoptosis.1-3
To date, this family is composed of seven receptor subtypes, named P2X1-P2X7, all of which have been cloned.
The various P2X receptors show distinct expression patterns. P2X1-6 receptors have been found in the central and peripheral nervous system, while the P2X7 receptor is found in cells of the immune system, particularly in antigen-presenting cells, and microglia.
The P2X7 receptor mediates the release of proinflamatory cytokines and stimulation of transcription factors and may also play an important role in apoptosis.1-3
制备和贮存
溶解方法
50 µl double distilled water (DDW).
保存方式
The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
数据库链接
Entrez-Gene ID
29665
UniProt ID
Q64663
研究资源识别码
AB_2040067.
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