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APC Anti-ABCB11/BSEP antibody [EPR22670-64]
品牌： Abcam
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对比
咨询纯度：
Protein A purified
来源宿主：
Rabbit
产品介绍
产品介绍
产品信息
荧光素标记
抗原名称
Catalyzes the transport of the major hydrophobic bile salts, such as taurine and glycine-conjugated cholic acid across the canalicular membrane of hepatocytes in an ATP-dependent manner, therefore participates in hepatic bile acid homeostasis and consequently to lipid homeostasis through regulation of biliary lipid secretion in a bile salts dependent manner (PubMed : 15791618, PubMed : 16332456, PubMed : 18985798, PubMed : 19228692, PubMed : 20010382, PubMed : 20398791, PubMed : 22262466, PubMed : 24711118, PubMed : 29507376, PubMed : 32203132). Transports taurine-conjugated bile salts more rapidly than glycine-conjugated bile salts (PubMed : 16332456). Also transports non-bile acid compounds, such as pravastatin and fexofenadine in an ATP-dependent manner and may be involved in their biliary excretion (PubMed : 15901796, PubMed : 18245269).
宿主
Rabbit
免疫原
Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.
简单描述
APC兔单克隆抗体[EPR22670-64] to ABCB11/BSEP
商品描述
Rabbit Recombinant Monoclonal ABCB11/BSEP antibody - conjugated to APC.
同种型
IgG
克隆号
EPR22670-64
克隆类别
单克隆
纯度
Protein A purified
形式
Liquid
研究领域
癌症
应用
实验应用
Target Binding Affinity, Antibody Labelling
背景
别名
BSEP, ABCB11, Bile salt export pump, ATP-binding cassette sub-family B member 11
研究领域
Signal Transduction Metabolism Plasma Membrane Channels Signal Transduction Metabolism Lipid metabolism Cancer Cancer Metabolism Metabolic signaling pathway Metabolism of lipids and lipoproteins Metabolism Pathways and Processes Metabolic signaling pathways Lipid and lipoprotein metabolism Lipid metabolism Neuroscience Processes
制备和贮存
存储溶液
pH: 7.4Preservative: 0.02% Sodium azideConstituents: 98% PBS, 1% BSA
保存方式
Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at +4°C. Avoid freeze / thaw cycle. Store In the Dark.
数据库链接
UniProt ID
O95342
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