APC Anti-Aquaporin 1 antibody [EPR20325]

Forms a water channel that facilitates the transport of water across cell membranes, playing a crucial role in water homeostasis in various tissues (PubMed : 1373524, PubMed : 23219802). Could also be permeable to small solutes including hydrogen peroxide, glycerol and gases such as amonnia (NH3), nitric oxide (NO) and carbon dioxide (CO2) (PubMed : 16682607, PubMed : 17012249, PubMed : 19273840, PubMed : 33028705, PubMed : 8584435). Recruited to the ankyrin-1 complex, a multiprotein complex of the erythrocyte membrane, it could be part of a CO2 metabolon, linking facilitated diffusion of CO2 across the membrane, anion exchange of Cl(-)/HCO3(-) and interconversion of dissolved CO2 and carbonic acid in the cytosol (PubMed : 17012249, PubMed : 35835865). In vitro, it shows non-selective gated cation channel activity and may be permeable to cations like K(+) and Na(+) in vivo (PubMed : 36949749, PubMed : 8703053).

Rabbit

Synthetic peptide. This information is proprietary to Abcam and/or its suppliers.

APC兔单克隆抗体[EPR20325] to Aquaporin 1

IgG

EPR20325

单克隆

Protein A purified

0.5 mg/mL 本产品的浓度可能与批次相关

Liquid

神经科学

Target Binding Affinity, Antibody Labelling

CHIP28, AQP1, Aquaporin-1, AQP-1, Aquaporin-CHIP, Channel-like integral membrane protein of 28 kDa, Urine water channel

pH: 7.40Preservative: 0.02% Sodium azideConstituents: 98% PBS, 1% BSA

P29972