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产品介绍
产品信息
商品描述
APS6-45 inhibits RAS/MAPK signaling and exhibits anti-tumor activity.
分子量
548.4
纯度
98%
可溶性
DMSO:240mg/mL (437.67mM)
In vitro(体外研究)
APS6-45 (1 μM; 1 h) strongly inhibits RAS pathway activity signaling in human MTC cell lines TT and MZ-CRC-1[1].
In vivo(体内研究)
APS6-45 did not affect body weight of dosed(10 mg/kg) mice after 30 d.APS6-45 (0.1-160 mg/kg; a single p.o.) does not cause detectable toxic effects in mice[1].
背景
分子式
C23H16F8N4O3
CAS号
2188236-41-9
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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