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Anti-ASIC1 Antibody
品牌： Alomone
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对比
咨询纯度：
Affinity purified on immobilized antigen.
反应种属：
H, M, R
产品介绍
产品介绍
产品信息
宿主
兔
简单描述
A Rabbit Polyclonal Antibody to ASIC1 Channel
商品描述
Each antibody ordered from Alomone Labs is supplied with its corresponding control peptide (antigen), free of charge. A Rabbit Polyclonal Antibody to ASIC1 Channel
纯度
Affinity purified on immobilized antigen.
组成成分
酸敏感通道蛋白抗体;磷酸盐缓冲液;防腐剂(0.05%叠氮化钠溶液)
应用
实验应用
IC, IH, IP, WB
反应种属
H, M, R
背景
背景
ASIC1 is a member of a family of Na+ channels that are activated by external protons. The family includes another three members ASIC2, ASIC3 and ASIC4.
The ASICs are in fact part of a larger superfamily termed epithelial Na+ channels (EnaC) and share with it the same basic characteristics: two transmembrane spanning domains, a large extracellular domain and short intracellular N and C termini.
There are two recognized splice variants of the ASIC1 gene that differ on their N-termini, ASIC1a and ASIC1b that have different tissue distributions and functions.
The ASIC1 responds to a decrease in extracellular pH with an inward cation current that is quickly inactivated despite the continuous presence of protons in the medium.
Lately, ASIC1 has been implicated in processes such as learning and memory in the central nervous system.
The ASICs are in fact part of a larger superfamily termed epithelial Na+ channels (EnaC) and share with it the same basic characteristics: two transmembrane spanning domains, a large extracellular domain and short intracellular N and C termini.
There are two recognized splice variants of the ASIC1 gene that differ on their N-termini, ASIC1a and ASIC1b that have different tissue distributions and functions.
The ASIC1 responds to a decrease in extracellular pH with an inward cation current that is quickly inactivated despite the continuous presence of protons in the medium.
Lately, ASIC1 has been implicated in processes such as learning and memory in the central nervous system.
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