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ASIC2A ANTIBODY ATTO 594
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抗原
偶联物
激发/发射光谱
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产品详细信息
Reconstitution: 50 µL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
ACCN1 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member encoded by this protein may play a role in neurotransmission. In addition, a heteromeric association between this member and ACCN3 (variant 1) has been observed to co-assemble into proton-gated channels sensitive to gadolinium.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: acid sensing (proton gated) ion channel 2; acid sensing ion channel 2; acid-sensing (proton-gated) ion channel 2; Acid-sensing ion channel 2; ACNN1; Amiloride-sensitive brain sodium channel; Amiloride-sensitive brain sodium channel 2; Amiloride-sensitive cation channel 1, neuronal; amiloride-sensitive cation channel 1, neuronal (degenerin); Amiloride-sensitive cation channel neuronal 1; ASIC2; BNC1; Brain sodium channel 1; degenerin; Mammalian degenerin homolog; MDEG; neuronal amiloride-sensitive cation channel 1
基因别名: ACCN; ACCN1; ACIC2; ASIC2; ASIC2a; BNAC1; BNaC1a; BNC1; BNC1k; hBNaC1; MDEG; MDEG1; MDEG2
UniProt ID:(Human) Q16515, (Rat) Q62962, (Mouse) Q925H0
Entrez Gene ID:(Human) 40, (Rat) 25364, (Mouse) 11418
参考图片
Expression of ASIC2a in rat cerebellum and spinal cord - Immunohistochemical staining of perfusion-fixed frozen rat brain and spinal cord sections using Anti-ASIC2a-ATTO Fluor-594 Antibody (#ASC-012-AR), (1:60). A. Staining in rat cerebellum sections reveals ASIC2a expression (red) in the molecular layer (MOL) of the cerebellar cortex. B. Staining in rat spinal cord sections shows labeling (red) of neuronal soma (horizontal arrow) in the ventral horn of the spinal cord. DAPI (blue) is used as counterstain in A and B.