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ASIC4 ANTIBODY
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产品详细信息
Reconstitution: 50 µL or 0.2 mL double distilled water (DDW), depending on the sample size. The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20C. The reconstituted solution can be stored at 4C for up to 1 week. For longer periods, small aliquots should be stored at -20C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
靶标信息
This gene belongs to the superfamily of acid-sensing ion channels, which are proton-gated, amiloride-sensitive sodium channels. These channels have been implicated in synaptic transmission, pain perception as well as mechanoperception. This gene is predominantly expressed in the pituitary gland, and was considered a candidate for paroxysmal dystonic choreoathetosis (PDC), a movement disorder, however, no correlation was found between mutations in this gene and PDC. Alternative splicing at this locus results in two transcript variants encoding different isoforms.
仅用于科研。不用于诊断过程。未经明确授权不得转售。
生物信息学
蛋白别名: acid sensing (proton gated) ion channel family member 4; acid sensing ion channel family member 4; acid-sensing (proton-gated) ion channel family member 4; Acid-sensing ion channel 4; Amiloride-sensitive cation channel 4; Amiloride-sensitive cation channel 4, pituitary; amiloride-sensitive cation channel family member 4, pituitary; ASIC4; brain sodium channel 4; MGC17248; MGC24860; putative acid-sensing ion channel; spinal chord ASIC; Spinal cord ASIC
基因别名: ACCN4; ASIC4; BNAC4; Spasic
UniProt ID:(Human) Q6PIN9, (Rat) Q9JHS6, (Mouse) Q7TNS7
Entrez Gene ID:(Human) 55515, (Rat) 63882, (Mouse) 241118
参考图片
Western blot analysis of mouse ND7/23 neuroblastoma x rat DRG neuron hybrid cell line (lanes 1 and 3) and rat brain (lanes 2 and 4) lysates: - 1,2. Anti-ASIC4 Antibody (#ASC-015), (1:200).3,4. Anti-ASIC4 Antibody , preincubated with ASIC4 Blocking Peptide (#BLP-SC015).
Western blot analysisof rat DRG lysates: - 1. Anti-ASIC4 Antibody (#ASC-015), (1:200). 2. Anti-ASIC4 Antibody , preincubated with ASIC4 Blocking Peptide (#BLP-SC015).