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AT-007
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产品介绍
产品介绍
产品信息
抗原名称
Aldose reductase:100 pM
商品描述
AT-007 is an orally active CNS penetrant Aldose Reductase inhibitor for the treatment of Galactosemia (IC50: 100 pM). It reduces toxic galactitol levels and prevents disease complications in GALT deficiency rats.
分子量
425.4
纯度
98%
可溶性
DMSO:35.71 mg/mL (83.94 mM)
In vivo(体内研究)
AT-007 significantly reduces galactitol levels in GALT null rats in all target tissues ( liver, brain, and plasma), and does not increase galactose or Gal-1P levels [2].
背景
分子式
C17H10F3N3O3S2
CAS号
2170729-29-8
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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