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产品介绍
产品介绍
产品信息
荧光素标记
Unconjugated

氨基酸序列
Phe29-Ala258, with C-terminal 8*His

分子量
45-57 kDa(Reducing)

纯度
>95% by SDS-PAGE

内毒素水平
<0.1EU/μg

性状
Lyophilized powder

表达系统
HEK293

缓冲体系
PBS, pH7.4

种属
Cynomolgus

电泳JSON
[{"imgUrl":"https://univ-njua.oss-cn-shanghai.aliyuncs.com/prod/202208/21d82bef963244418118b7f4a6f4dded.png","description":"2μg(R: reducing conditions, N: non-reducing conditions)."}]

背景
别名
VTCN1

背景
V-set domain-containing T-cell activation inhibitor 1 (VTCN1) is also known as Immune costimulatory protein B7-H4, Protein B7S1, T-cell costimulatory molecule B7x, B7H4, which belongs to the immunoglobulin superfamily and BTN/MOG family. VTCN1 contains two Ig-like V-type (immunoglobulin-like) domains. The expression of VTCN1 is up-regulated by IL6 and IL10 and is inhibited by GM-CSF and IL4 on antigen-presenting cells (APCs). VTCN1/B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. VTCN1 involved in promoting epithelial cell transformation.

制备和贮存
溶解方法
Reconstitute at 0.1-1 mg/ml according to the size in ultrapure water after rapid centrifugation.

保存方式
· 12 months from date of receipt, lyophilized powder stored at -20 to -80℃.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
· 3 months, -20 to -80℃ under sterile conditions after reconstitution.
· 1 week, 2 to 8℃ under sterile conditions after reconstitution.
· Please avoid repeated freeze-thaw cycles.
数据库链接
Accession
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