

品牌: SantaCruz








来源宿主:
mouse
mouse
实验应用:
WB, IP, IF, ELISA
WB, IP, IF, ELISA
产品介绍
产品信息
宿主
mouse

简单描述
band 3抗体(BIII 136)是小鼠单克隆IgG2a κ, 在1篇文献中引用,规格为200 µg/ml
raised against full length purified band 3 of human origin
推荐用于 human 来源的band 3 WB, IP, IF 和 ELISA检测
m-IgG2a BP-HRP 是band 3 Antibody (BIII 136) for WB首选应用二抗. 这些试剂现在以套装形式提供band 3 Antibody (BIII 136) (见下方订购信息). Band 3, also designated AE1, is an erythrocyte membrane glycoprotein that contributes to cell stuctural integrity and mediates exchange of chloride and bicarbonate across the phospholipid bilayer. The diverse functions of the approximately 900 amino acid protein are mediated by two distinct domains. The amino terminal domain, also known as cdb3 for cytoplasmic domain of erthrocyte membrane band 3, acts as an attachment site for the erythrocyte skeleton by binding ankyrin (2-4). The carboxy-terminal, membrane-associated domain carries out exchange transport of anions (2,5). Degradation of band 3 can generate an aging antigen known as senescent cell antigen, or SCA, which is expressed on old cells and marks them for removal by the immune system. An isoform of band 3, which lacks the first 65 amino acids and does not bind ankryin, is expressed in kidney.For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

克隆类别
Replacement monoclonal antibody for: sc-20557, sc-20559, sc-20657, sc-130970.

组成成分
IGG-免疫球蛋白G型抗体

基因

应用
实验应用
WB, IP, IF, ELISA

数据库链接
Entrez-Gene ID
6521

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