BAPTA四钾盐

BAPTA tetrapotassium salt (1,2-bis-(o-Aminophenoxy)-ethane-N,N,N’,N’-tetraacetic acid•4K) is a selective calcium chelator with 105-fold greater affinity for Ca²⁺ than for Mg²⁺. This product is a high quality and sensitive compound for calcium signaling studies, investigation of signal transduction including apoptotic cascades, and neuroscience research. BAPTA and its derivatives are calcium chelators commonly used to form calcium buffers with well-defined calcium concentrations.
BAPTA free acid is not cell permeable and is useful for manipulating extracellular Ca²⁺ levels. BAPTA is closely related to the well-known chelator EGTA [ethylene glycol bis(beta-aminoethyl ether)-N,N,N’,N’-tetraacetic acid] , but is less effected by pH changes and are more efficient at taking up and releasing Ca²⁺.

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