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产品介绍
产品信息
商品描述
BC-1471 is a novel selective antagonist of deubiquitinase STAM-binding protein (STAMBP), decreasing NALP7 protein levels and suppressing IL-1β release after TLR agonism.
分子量
504.6
纯度
98%
可溶性
DMSO:5.05 mg/ml (10 mM),H2O:Insoluble
In vitro(体外研究)
A small-molecule inhibitor of STAMBP deubiquitinase activity, BC-1471, decreases NALP7 protein levels and suppresses IL-1β release after TLR agonism.?These findings describe a unique pathway of inflammasome regulation with the identification of STAMBP as a potential therapeutic target to reduce pro-inflammatory stress.
背景
分子式
C27H28N4O4S
CAS号
896683-78-6
制备和贮存
保存方式
Store at -20℃ for one year（Powder）；Store at 2-4℃ for two weeks；Store at -20℃ for six months after dissolution.
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